Xanax (alprazolam) may be helpful for PTSD (post traumatic stress disorder), but it is not the first choice treatment for PTSD. Benzodiazepines are not recommended in PTSD, as there is a high occurence of drug abuse with PTSD, and benzodiazepines are highly addictive. Better choices for medication treatment for PTSD include SSRIs (selective serotonin reuptake inhibitors) and SNRIs (serotonin norepinephrine reuptake inhibitors). Oftentimes, PTSD treatment with medications requires multiple medications to treat the different symptoms that occur in PTSD.