Hypervigilance is a state of hyperarousal often seen in post traumatic stress disorder (PTSD), where you are constantly scanning your environment for any signs of a threat. You are on-guard and suspicious of any danger that may be lurking. The best medications for hypervigilance include alpha adrenergic agonists, alpha blockers, and beta blockers.
Alpha adrenergic agonists include the medications clonidine (Catapres) and guanfacine (Tenex). Alpha adrenergic agonists help to decrease hypervigilance and hyperarousal by reducing the production of adrenaline, thereby reducing the hyperarousal symptoms (alpha adrenergic agonists decrease the heart rate and decrease the blood pressure).
Alpha blockers include the medication prazosin (Minipress). Alpha blockers work by blocking the adrenaline receptors, and are prescribed to treat the trauma nightmares associated with PTSD.
Beta blockers include the medications propranolol (Inderal) and atenolol (Tenormin). Beta blockers work by blocking the effects of adrenaline, and reduce the hyperarousal symptoms (beta blockers decrease the heart rate and decrease the tremors).