Hi. It’s Jenny at AnxietyBoss.com. Our question today is from Donna in Columbus, Ohio. Can Prozac affect my blood sugar levels?
Although Prozac serves as a superb drug for depression, little research has actually been done on its side effects on those who suffer from diabetes or those who are looking to reduce their blood sugar levels. Now because of this, many doctors who prescribe anti-depressants to their patients are not aware of the possibility that SSRIs or Selective Serotonin Reuptake Inhibitors can actually lower blood sugar levels.
When this occurs, patients may find that it’s necessary to decrease the amount of diabetes medication that they’re taking. In accordance to Prozac’s drug label which is posted on the FDA website, in patients with diabetes, Prozac may alter glycemic control.
Hypoglycemia has occurred during therapy with Prozac and Hyperglycemia has developed following discontinuation of the drug. As is true with many other types of medication when taken concurrently by patients with diabetes, insulin and oral hypoglycemic dosage may need to be adjusted when therapy with Prozac is instituted or discontinued.

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