Yes, you can control your fight or flight response. If you have an overactive fight or flight response, then you can decrease the response by addressing your stress and anxiety. There are various ways to decrease your stress and anxiety, such as diaphragmatic breathing, progressive muscle relaxation, yoga, exercise, acupuncture, massage, guided imagery, meditation, natural supplements, and martial arts. If your fight or flight response is triggered by an anxiety disorder, then the previously mentioned modalities can augment primary treatments to address the anxiety disorder, such as CBT (cognitive behavioral therapy) and prescription medication treatment.
If you have an underactive fight or flight response, and want more adrenaline coursing through your bloodstream, then there are ways to increase your fight or flight response as described here.
In summary, you can control your fight or flight response by either decreasing it through the reduction of stress and anxiety, or increasing it through the use of various techniques to increase the release of adrenaline, a hormone which mediates the fight or flight response.